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Definitions

antagonist

[an-tag-uh-nist] / ænˈtæg ə nɪst /


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Finerenone is a non-steroidal mineralocorticoid receptor antagonist currently approved to treat CKD associated with type 2 diabetes.

From Science Daily • Jun. 8, 2026

Robert Pattinson portrays the cruel and arrogant antagonist Antinous, who has own eyes fixed firmly on the queen while her husband is still away.

From BBC • May 5, 2026

Like Li, he was upset by the "ugly" portrayal of his likeness as a "sleazy" antagonist in the show.

From Barron's • Apr. 24, 2026

The road is looking similarly tough for Ed Gallrein, whom the president backs to take out his longtime antagonist, Kentucky Rep. Thomas Massie.

From The Wall Street Journal • Apr. 23, 2026

He liked that there was a new protagonist in the same world and that the previous protagonist was now the antagonist.

From "Healer of the Water Monster" by Brian Young




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