symptoms

An investigation into the mother showed that she had required periods of hospital treatment herself for symptoms that were never fully medically explained, including “pseudo-seizures,” the authenticity of which was questioned by both clinicians and her own family.

This is described by the NHS as “a rare form of child abuse”, where a parent exaggerates or deliberately causes symptoms of illness in a child.

The results from the phase 2b randomized clinical trial, published November 20th in Annals of Neurology, build on more than a decade of research spurred by anecdotal reports from patients with LD who said their symptoms improved after consuming a couple alcoholic drinks.

In the trial of more than 100 patients, a single dose of sodium oxybate significantly improved symptoms of patients with alcohol-responsive LD without causing serious side effects.

Sodium oxybate showed no significant changes from placebo in LD patients whose symptoms do not improve with alcohol.