basket-case

defenseless destitute forlorn impotent paralyzed powerless unable unprotected vulnerable weak

incapable incompetent

abandoned debilitated dependent exposed feeble forsaken friendless handcuffed inefficient inexpert infirm invalid over a barrel pinned prostrate shiftless tapped tapped out unfit up creek without paddle with hands tied

able capable fit potent powerful secure strong

competent enterprising independent resourceful skilled

a bundle of nerves nervous wreck ninnyhammer